Institute of Research on Cancer and Aging in Nice (IRCAN)
Jacques Pouysségur, CNRS Research Director Emeritus, graduated from an Engineering School in Biochemistry of the University of Lyon, where he obtained his PhD in 1972. He spent two years as a post-doctoral scientist at the National Cancer Institute of NIH (USA) and established his own research group in 1978 at the CNRS Biochemistry Centre of the University of Nice. After directing the CNRS Institute of Signalling, Developmental Biology and Cancer Research up to 2008, his team joined the new Research Institute of Cancer & Aging (IRCAN) in Nice and the Biomedical Department of the Centre Scientifique of Monaco (CSM). Jacques Pouysségur has previous experience in bacterial and somatic cell genetics, metabolism, Na-H exchanger, pH regulation, G protein-coupled receptors and MAP kinase signalling in the context of growth control in mammalian cells. In the last 25 years his group developed a strong interest in hypoxia signalling, oxygen and nutrient sensing, angiogenesis, autophagy amino-acid transporters, oxidative stress, cancer metabolism, Warburg effect and immune-suppression. He is member of AACR, EACR, EMBO, the French and European Academy of Sciences and the past President of the International Advisory board of the National Cancer Institute.