Renal Aging

The age of the kidney depends on the gradual decrease in kidney structure and function that develops with age. This procedure includes a decrease in the number of functional nephrons, a decrease in glomerular filtration rate (GFR), and a decrease in the ability to concentrate urine and regulate electrolyte balance. Structural changes such as glomerulosclerosis, interstitial fibrosis, and arteriosclerosis are also common. These changes are part of normal aging, but can increase the risk of chronic kidney disease (CKD), especially in combination with diseases such as hypertension and diabetes. Understanding the age of the kidneys is important for treating kidney health in older people and is to prevent functional declines.

  • Age-Related Decline in Glomerular Filtration Rate (GFR)
  • Drug Dosing and Nephrotoxicity in Aged Kidneys
  • Biomarkers of Renal Aging
  • Dialysis and Kidney Replacement Therapy in Older Adults
  • Renovascular Aging and Endothelial Dysfunction
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